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  2. Quality of life and Comprehensive Geriatric Assessment (CGA) in older adults receiving Accelerated Partial Breast Irradiation (APBI) using a single fraction of Multi-Catheter Interstitial High-Dose Rate Brachytherapy (MIB). The SiFEBI phase I/II trial.

Quality of life and Comprehensive Geriatric Assessment (CGA) in older adults receiving Accelerated Partial Breast Irradiation (APBI) using a single fraction of Multi-Catheter Interstitial High-Dose Rate Brachytherapy (MIB). The SiFEBI phase I/II trial.

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  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function: Creation of dynamic property DatabaseCondition::$stringVersion is deprecated in DatabaseCondition->compile() (line 1887 of /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function: Creation of dynamic property DatabaseCondition::$stringVersion is deprecated in DatabaseCondition->compile() (line 1887 of /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function: Creation of dynamic property DatabaseCondition::$stringVersion is deprecated in DatabaseCondition->compile() (line 1887 of /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function: Creation of dynamic property DatabaseCondition::$stringVersion is deprecated in DatabaseCondition->compile() (line 1887 of /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function: Return type of DateObject::__wakeup() should either be compatible with DateTime::__wakeup(): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in include_once() (line 158 of /home/gerontopcx/www/sites/all/modules/date/date_api/date_api.module).
  • Deprecated function: Return type of DateObject::format($format, $force = false) should either be compatible with DateTime::format(string $format): string, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in include_once() (line 158 of /home/gerontopcx/www/sites/all/modules/date/date_api/date_api.module).
  • Deprecated function: Return type of DateObject::setTimezone($tz, $force = false) should either be compatible with DateTime::setTimezone(DateTimeZone $timezone): DateTime, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in include_once() (line 158 of /home/gerontopcx/www/sites/all/modules/date/date_api/date_api.module).
  • Deprecated function : Creation of dynamic property SelectQuery::$alterTags is deprecated dans SelectQuery->addTag() (ligne 978 dans /home/gerontopcx/www/includes/database/select.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property SelectQuery::$alterMetaData is deprecated dans SelectQuery->addMetaData() (ligne 997 dans /home/gerontopcx/www/includes/database/select.inc).
  • Deprecated function : Creation of dynamic property SelectQuery::$alterTags is deprecated dans SelectQuery->addTag() (ligne 978 dans /home/gerontopcx/www/includes/database/select.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property SelectQuery::$alterMetaData is deprecated dans SelectQuery->addMetaData() (ligne 997 dans /home/gerontopcx/www/includes/database/select.inc).
  • Deprecated function : Creation of dynamic property SelectQuery::$alterTags is deprecated dans SelectQuery->addTag() (ligne 978 dans /home/gerontopcx/www/includes/database/select.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property SelectQuery::$alterTags is deprecated dans SelectQuery->addTag() (ligne 978 dans /home/gerontopcx/www/includes/database/select.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property SelectQuery::$alterTags is deprecated dans SelectQuery->addTag() (ligne 978 dans /home/gerontopcx/www/includes/database/select.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property SelectQuery::$alterTags is deprecated dans SelectQuery->addTag() (ligne 978 dans /home/gerontopcx/www/includes/database/select.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property SelectQuery::$alterTags is deprecated dans SelectQuery->addTag() (ligne 978 dans /home/gerontopcx/www/includes/database/select.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property SelectQuery::$alterTags is deprecated dans SelectQuery->addTag() (ligne 978 dans /home/gerontopcx/www/includes/database/select.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
  • Deprecated function : Creation of dynamic property DatabaseCondition::$stringVersion is deprecated dans DatabaseCondition->compile() (ligne 1887 dans /home/gerontopcx/www/includes/database/query.inc).
TitreQuality of life and Comprehensive Geriatric Assessment (CGA) in older adults receiving Accelerated Partial Breast Irradiation (APBI) using a single fraction of Multi-Catheter Interstitial High-Dose Rate Brachytherapy (MIB). The SiFEBI phase I/II trial.
Publication TypeJournal Article
Year of Publication2021
AuthorsBoulahssass R, Chand M-E, Gal J, Dittlot C, Schiappa R, Rambaud C, Gonfrier S, GuÉrin O, Hannoun-Levi JMichel
JournalJ Geriatr Oncol
Volume12
Issue7
Pagination1085-1091
Date Published2021 09
ISSN1879-4076
Mots-clésActivities of Daily Living, Aged, Aged, 80 and over, Brachytherapy, Breast Neoplasms, Catheters, Female, Geriatric Assessment, Humans, Quality of Life
Résumé

OBJECTIVES: The SiFEBI trial demonstrated that a post-operative Multicatheter Interstitial Brachytherapy (MIB) appears feasible and with acceptable toxicity in older adults aged 70 years and older presenting with low-risk breast cancer. The aim of the present ancillary study was to analyze the quality of life and Comprehensive Geriatric Assessment (CGA) domains within 6 months in older adults receiving Accelerated Partial Breast Irradiation (APBI) using a single fraction of MIB.MATERIALS AND METHODS: From 11/2012 to 09/2014, 37 patients were included and 26 were evaluable. Patients (pts) aged 70 years and older with a Balducci score of 1 or 2 and presenting with low-risk breast cancer were prospectively enrolled in this phase I/II trial (NCT01727011). After lumpectomy, intra-operative catheter implantation was performed for post-operative APBI after pathological findings. Quality of life (QoL) evaluation and CGA were scheduled at baseline and 1, 3, and 6 months after APBI. Autonomy decline was defined as a 1-point decrease in Activities of Daily Living (ADL).RESULTS: Mean age was 77 years. Within the first 6 months of follow-up, no autonomy decline was observed in ADL, 3 patients had an autonomy decline in Instrumental Activities of Daily Living (IADL) and 2 patients had a slower gait speed but no changes in cognitive function, nutritional status, and depression screening. Global QoL was quite similar at baseline compared to 1, 3, and 6 months. No differences were observed for functional items.CONCLUSION: APBI based on a single fraction of MIB in older adults with low-risk breast cancer appears to be feasible with a minimal loss of autonomy regarding IADL, no loss of autonomy in ADL, an acceptable decrease in other CGA domains, and with no impact on global quality of life.
DOI10.1016/j.jgo.2021.04.009
Alternate JournalJ Geriatr Oncol
PubMed ID33994151